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Embryonic vs. adult myogenesis: challenging the 'regeneration recapitulates development' Free
John Wang and Irina Conboy*
Department of Bioengineering, University of California, Berkeley, 174 Stanley Hall, Berkeley, CA 94720-1762, USA *Correspondence to:Irina Conboy, E-mail: iconboy@berkeley.edu
J Mol Cell Biol, Volume 2, Issue 1, February 2010, 1-4,  https://doi.org/10.1093/jmcb/mjp027

A popular theory in the stem cell field is that "regeneration recapitulates development" or that adult stem cells function similarly to embryonic ones. In a recent Nature article, Lepper et al. questioned this approach, highlighting the differences in requirements for Pax7 during myogenesis for embryonic, juvenile and adult muscle.

Volume 2, Issue 1
February 2010